Background:

The kinesin family of motor proteins comprise at least two forms of conventional kinesin, which are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells . The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains. While the kinesin heavy chain contains the motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. Kinesin-driven vesicle motility is dependent upon kinectin 1, a kinesin-binding protein . Kinectin 1, also known as kinesin receptor, is an integral membrane protein in the ER . Despite the kinesin-kinectin 1 interaction, a great deal of debate surrounds the involvement of kinectin 1 in microtubule-dependent transport .

Specificity:

KTN1 polyclonal antibody detects endogenous levels of KTN1 protein.

Alternative names:

Kinectin; CG-1 antigen; Kinesin receptor; KTN1; CG1; KIAA0004

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human KTN1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 156 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com