Background:

IFN-inducible T cell a chemoattractant (I-TAC), also designated βR1, H174, SCYB9B, Scyb11 (mouse), IP-9 or CXCL11, is a member of the CXC chemo-kine family and is expressed in IFN-gamma-treated astrocytes, monocytes, keratin-ocytes, bronchial epithelial cells and neutrophils. The gene encoding I-TAC maps to human chromosome 4q21.2. I-TAC and two related proteins, IFN-induced protein of 10 kDa (IP-10) and monokine induced by IFN-gamma (MIG), belong to the non-glutamate-leucine-arginine motif CXC chemokine family and act solely through the CXCR-3 receptor for potent attraction of T lymphocytes. I-TAC is assumed to be involved in inflammatory diseases characterized by the presence of activated T cells.

Specificity:

CXCL11 polyclonal antibody detects endogenous levels of CXCL11 protein.

Alternative names:

Beta-R1; betaR1; C-X-C motif chemokine 11; Chemokine (C-X-C motif) ligand 11; Chemokine C-X-C motif ligand 11; CXC11; CXCL11; CXL11_HUMAN; H174; I TAC; I-TAC; Interferon gamma inducible protein 9; Interferon gamma-inducible protein 9; Interferon inducible T cell alpha chemoattractant; Interferon-inducible T-cell a chemoattractant I-TAC; Interferon-inducible T-cell alpha chemoattractant; IP 9; IP-9; IP9; ITAC; MGC102770; SCYB11; SCYB9B; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys) member 11; small inducible cytokine subfamily B (Cys-X-Cys) member 9B; Small inducible cytokine subfamily B, member 11; Small inducible cytokine subfamily B, member 9B; Small-inducible cytokine B11;

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human CXCL11.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 10 kDa

Applications:

IHC

Usage:

IHC 1:100 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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