GPD1 polyclonal antibody BS7810
Specifications
| 50ul/100ul |
Background:
Voltage-gated sodium channels drive the initial depolarization phase of the cardiac action potential, therefore, critically determine conduction of excitation through the heart. As a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, glycerol-3-phosphate dehydrogenase 1 (GPD1) is a 349 amino acid cytoplasmic protein that catalyzes the formation of glycerone phosphate and NADH from sn-glycerol 3-phosphate and NAD+. Inhibited by zinc ions and sulfate, GPD1 exists as a homodimer and may have similar functions as GPD1L (glycerol-3 phosphate dehydrogenase like). GPD1L is thought to affect trafficking of the cardiac sodium current to the cell surface and mutations in the gene encoding GPD1L are thought to be involved in sudden infant death syndrome (SIDS).
Specificity:
GPD1 polyclonal antibody detects endogenous levels of GPD1 protein.
Alternative names:
cytoplasmic; FLJ26652; G3PD; Gdc-1; Gdc1; Gdp1; Glycerol 3 phosphate dehydrogenase 1; Glycerol 3 phosphate dehydrogenase cytosolic; Glycerol 3 phosphate dehydrogenase soluble; Glycerol-3-phosphate dehydrogenase [NAD+]; Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; Glycerol-3-phosphate dehydrogenase 1 (soluble); Glycerol-3-phosphate dehydrogenase; Glycerol-3-phosphate dehydrogenase, soluble; Glycerphosphate dehydrogenase; GPD-C; gpd1; Gpd1 protein; Gpd3; GPDA_HUMAN; Gpdc; GPDH; GPDH-C; Gpdhc; HTGTI; KIAA4010; MGPD; mKIAA4010;
Species reactivity:
Human,Mouse,Rat
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Recombinant full length Human GPD1.
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Molecular weight:
~ 38 kDa
Applications:
WB IHC
Usage:
WB: 1:500~1:2000 IHC: 1:50~1:200
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
