Background:

The Lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include hepatic lipase (HL), endothelial lipase (EDL or EL), lipoprotein lipase (LPL), pancreatic lipase (PL), gastric lipase (GL) and LCAT. These family members play a crucial role in the metabolism of lipids. Defects in LPL may cause chylomicronemia syndrome or a form of lipoprotein lipase deficiency characterized by hypertriglyceridemia. Endothelial lipase, which also is known as endothelial cell-derived lipase, has both triglyceride and phospholipase activity. This protein, which is synthesized in endothelial cells, can bind heparin. It is expressed primarily in placenta, liver, thyroid, kidney, lung, testis and ovary tissue.

Specificity:

LIPG polyclonal antibody detects endogenous levels of LIPG protein.

Alternative names:

EDL; EL; Endothelial cell-derived lipase; Endothelial lipase; Endothelial lipase precursor; Lipase endothelial; LIPE_HUMAN; LIPG; Lipoprotein lipase H; PL; PRO719;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human LIPG.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 57 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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