Background:

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.

Specificity:

NPC2 polyclonal antibody detects endogenous levels of NPC2 protein.

Alternative names:

EDDM1; Epididymal protein 1; Epididymal secretory protein; Epididymal secretory protein E1 [Precursor]; Epididymal secretory protein E1; HE1; Human epididymis-specific protein 1; MGC1333; Niemann-Pick disease type C2; Niemann-Pick disease type C2 protein; NP-C2; NPC2; NPC2_HUMAN; Tissue specific secretory protein;

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human NPC2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~17 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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