Background:

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.

Specificity:

GJB3 polyclonal antibody detects endogenous levels of GJB3 protein.

Alternative names:

Connexin 31; Connexin-31; Connexin31; CX 31; Cx31; CXB3_HUMAN; DFNA 2; DFNA2; DFNA2B; EKV; FLJ22486; Gap junction beta 3 protein; Gap junction beta-3 protein; Gap junction protein beta 3 31kDa; Gap junction protein beta 3; GJB 3; Gjb3; MGC102938;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human GJB3.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~31 kDa

Applications:

WB

Usage:

WB 1:200 - 1:500

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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