Background:

IFIT3 (interferon-induced protein with tetratricopeptide repeats 3), also known as IRG2, IFI60, IFIT4, ISG60 or RIG-G, is a 490 amino acid protein that contains eight TPR repeats and may play a role in cell cycle regulation and cellular proliferation. The gene encoding IFIT3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Specificity:

IFIT3 polyclonal antibody detects endogenous levels of IFIT3 protein.

Alternative names:

CIG-49;cig41;GARG-49;IFI60;IFIT4;IRG2;ISG60;P60;RIG-G

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of mouse IFIT3

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

60kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:1000 IHC 1:100 - 1:200 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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