Background:

Siglec-E (sialic acid binding Ig-like lectin E), also known as Cd170, Siglec5, Siglec9, Siglecl1 or mSiglec-E, is a 467 amino acid murine protein that localizes to the membrane and contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed at high levels in heart, liver and spleen and found at lower levels in lung and kidney, Siglec-E exists as a disulfide-linked homodimer that acts as a cell adhesion molecule which mediates sialic acid-dependent cell binding and is thought to play a role in immune system function. Siglec-E is subject to post-translational phosphorylation which may influence its protein binding capabilities.

Specificity:

SIGLEC9 polyclonal antibody detects endogenous levels of SIGLEC9 protein.

Alternative names:

Sialic acid-binding Ig-like lectin 9; Siglec-9; CDw329; Protein FOAP-9; CD329; SIGLEC9; UNQ668/PRO1302; Protein FOAP9

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant Protein of human SIGLEC9

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

50kDa

Applications:

WB,IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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