Background:

PHF19 (PHD finger protein 19), also known as PCL3 (polycomb-like 3), is a 580 amino acid protein that contains two PHD-type zinc fingers. PHF19 exists as three alternatively spliced isoforms and functions as a transcriptional repressor. Localizing to nucleus, PHF19 is ubiquitously expressed, with highest expression in placenta, skeletal muscle, kidney, liver and peripheral blood leukocytes. PHF19 is over-expressed in many types of cancers, including colon, skin, lung, rectal, cervical, uterus and liver cancers, as well as in cell lines derived from different stages of melanoma and in glioma cell lines.

Specificity:

PHF19 polyclonal antibody detects endogenous levels of PHF19 protein.

Alternative names:

PCL3; MTF2L1; TDRD19B;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human PHF19.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 66 kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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