Alternative names:

Host:

His-tag

Immunogen:

Reactivity:

E. coli Expression

Description:

Inclusion body;0.5mol Urea,PH=8

Specificity:

Carrier:pET30a-SNV-NP-His(C-term) Virus:nucleocapsid protein [Sin Nombre orthohantavirus]

Bio-MW:

1287bp;47kDa

Applications:

Reseach

Application dilution:

Reseach

Purification & Purity:

Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Storage & Stability:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background:

Sin Nombre virus (SNV) is the major cause of hantavirus cardiopulmonary syndrome (HCPS) in North America, a severe respiratory disease with a high fatality rate. SNV is carried by Peromyscus maniculatus, or deer mice, and human infection occurs following inhalation of aerosolized virus in mouse excreta or secreta, often in peri-domestic settings. Currently there are no FDA approved vaccines or therapeutics for SNV or any other hantaviruses, therefore prevention of infection is an important means of reducing the disease burden of HCPS. One approach for preventing HCPS cases is to prevent the spread of the virus amongst the rodent reservoir population through bait vaccination.

Note:

For research use only, not for use in diagnostic procedure.