Alternative names:

Host:

His-tag

Immunogen:

Reactivity:

E. coli Expression

Description:

Soluble protein;PBS,PH=7.4

Specificity:

Carrier:pET30a-SFSV-NP-His(C-term) Virus:Sandfly fever sicilian virus strain Sabin segment S

Bio-MW:

738bp;28kDa

Applications:

Reseach

Application dilution:

Reseach

Purification & Purity:

Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Storage & Stability:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background:

Sandfly fever Sicilian virus (SFSV) is one of the most widespread and frequently identified members of the genus Phlebovirus (order Bunyavirales, family Phenuiviridae) infecting humans. Being transmitted by Phlebotomus sandflies, SFSV causes a self-limiting, acute, often incapacitating febrile disease ("sandfly fever," "Pappataci fever," or "dog disease") that has been known since at least the beginning of the 20th century. Similarly to other pathogenic phleboviruses, SFSV suppresses the induction of the antiviral type I interferon (IFN) system in an NSs-dependent manner. SFSV NSs interfered with the TBK1-interferon regulatory factor 3 (IRF3) branch of the RIG-I signaling pathway but not with NF-κB activation.

Note:

For research use only, not for use in diagnostic procedure.