Alternative names:

Host:

His-tag

Immunogen:

Reactivity:

E. coli Expression

Description:

Inclusion body;0.5mol Urea,PH=8

Specificity:

Carrier: pET30a-LUJV-NP-His(C-term) Virus: Lujo virus segment S

Bio-MW:

1671bp;61KDa

Applications:

Reseach

Application dilution:

Reseach

Purification & Purity:

Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Storage & Stability:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background:

Lujo virus (LUJV), a new member of the family Arenaviridae and the first hemorrhagic fever associated arenavirus from the Old World discovered in three decades, was isolated in South Africa during an outbreak of human disease characterized by nosocomial transmission and an unprecedented high case fatality rate of 80% (4/5 cases). Full genome analyses of LUJV showed it to be unique and branching off the ancestral node of the Old World arenaviruses. The virus G1 glycoprotein sequence was highly diverse and almost equidistant from that of other Old World and New World arenaviruses, consistent with a potential distinctive receptor tropism. LUJV is a novel, genetically distinct, highly pathogenic arenavirus.

Note:

For research use only, not for use in diagnostic procedure.