Background:

Human CD28 is an important co-stimulatory molecule found on all CD4+ T cells and ~50% of CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA, and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, known as CD80 (B7-1) and CD86 (B7-2), are monomeric transmembrane glycoproteins.

Specificity:

Recognizes the CD28 protein.

Alternative names:

T-cell-specific surface glycoprotein CD28; TP44; CD28

Species reactivity:

Human

Host:

Mouse

Ig type:

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Human CD28 Ig fusion protein and HPB-MLT human tumor cells.

Purification & Purity:

Protein A purified mouse monoclonal antibody, >95% immunoglobulin by SDS-PAGE

Molecular weight:

~ 25 kDa

Applications:

FCM IHC-Fr IP T cell Co-stimulation

Usage:

Flow Cytometry (5 µg/ml) Frozen Sections (User-optimized) Immunoprecipitation (User-optimized) T cell Co-stimulation (User-optimized)

Storage:

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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