Phospho-Syk-Y525/526 Rabbit pAb (AMR00979N) AMR00979N

Product info:

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names:

SYK; p72-Syk

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Cell membrane, Cytoplasm, cytosol

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around Y525 & Y526 of human Syk (NP_003168.2).

Positive control:

Jurkat

AA Sequence:

NYYK

Purification:

Affinity purification

Molecular weight:

Calculated MW: 69kDa/72kDa Observed MW: 72kDa

Form:

Liquid

Applications:

WB (Mus musculus)

Dilution:

WB 1:500 - 1:2000 IP 1:50 - 1:100

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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