Phospho-CDK9-T186 Rabbit pAb (AMR01092N) AMR01092N

Product info:

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Alternative names:

CDK9; C-2k; CDC2L4; CTK1; PITALRE; TAK

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cytoplasm, Nucleus, PML body

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1).

Positive control:

NIH/3T3

AA Sequence:

RYTNR

Purification:

Affinity purification

Molecular weight:

Calculated MW: 42kDa/53kDa Observed MW: 43KDa

Form:

Liquid

Applications:

WB (Human fibrosarcoma cells, HeLa cells, Mus musculus)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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