Phospho-TSC2-T1462 Rabbit pAb (AMR01147N) AMR01147N

Product info:

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names:

LAM; PPP1R160; TSC4; TSC2; Tuberin; tuberin

Species reactivity:

Human, Mouse

Host:

Rabbit

Cellular localisation:

Cytoplasm, Membrane, Peripheral membrane protein

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around T1462 of human TSC2 (NP_000539.2).

Positive control:

MCF7

AA Sequence:

GYTIS

Purification:

Affinity purification

Molecular weight:

Calculated MW: 25kDa/187-200kDa Observed MW: 200KDa

Form:

Liquid

Applications:

WB (Rattus norvegicus)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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