Phospho-Histone H2A-S129 Rabbit pAb (APG03384N) APG03384N

Product info:

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Alternative names:

H2A1; SPT11

Species reactivity:

Human, Rat

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A.

Positive control:

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AA Sequence:

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Purification:

Affinity purification

Molecular weight:

Calculated MW: 14kDa

Form:

Liquid

Applications:

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Dilution:

IHC 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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