Phospho-Src-Y529 Rabbit pAb (AMR00866N) AMR00866N

Product info:

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names:

ASV; SRC1; THC6; c-SRC; p60-Src; SRC

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around Y529 of human Phospho-Src-Y529 (NP_005408.1).

Positive control:

HeLa

AA Sequence:

PQYQP

Purification:

Affinity purification

Molecular weight:

Calculated MW: 59kDa/60kDa Observed MW: 60KDa

Form:

Liquid

Applications:

WB (Human lung cancer cell, Mus musculus, Homo sapiens, Rattus norvegicus) IHC (Mus musculus) IF (Mus musculus, Rattus norvegicus)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com