Cathepsin D Rabbit mAb (AMR12779N) AMR12779N

Product info:

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Alternative names:

CLN10; CPSD; HEL-S-130P; Cathepsin D; CTSD

Species reactivity:

Human, Mouse

Host:

Rabbit

Cellular localisation:

Lysosome, Melanosome, Secreted, extracellular space

Isotype:

IgG

Immunogen:

A synthesized peptide derived from human Cathepsin D .

Positive control:

A375, HepG2, MCF7, Mouse brain, Mouse kidney, Mouse spleen

AA Sequence:

Email info@sobekbio.com for sequence

Purification:

Affinity purification

Molecular weight:

Calculated MW: 46kDa/28kDa Observed MW: 28KDa/44KDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com