Product info:

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

Alternative names:

ADLD; LMN; LMN2; LMNB; Lamin B1; LMNB1; lamin-B1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Lipid-anchor, Nucleoplasmic side, Nucleus inner membrane

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1).

Positive control:

HeLa, MCF7, Jurkat, L929, Mouse brain, Rat testis

AA Sequence:

RVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM

Purification:

Affinity purification

Molecular weight:

Calculated MW: 66kDa Observed MW: 68KDa/45KDa

Form:

Liquid

Applications:

WB (HepG2, Homo sapiens, Mus musculus, Rattus norvegicus) IP (Mus musculus) IHC (Mus musculus)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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