α-Smooth Muscle Actin (ACTA2) Rabbit pAb (APR17738N) APR17738N

Product info:

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names:

AAT6; ACTSA; MYMY5; ACTA2; actin

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cytoplasm, cytoskeleton

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-124 of human α-Smooth Muscle Actin (ACTA2) (NP_001135417.1).

Positive control:

Mouse large intestine, Rat stomach, Rat lung

AA Sequence:

MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQI

Purification:

Affinity purification

Molecular weight:

Calculated MW: 42kDa Observed MW: 42KDa

Form:

Liquid

Applications:

WB (Mus musculus, Rattus norvegicus, Homo sapiens) IF (Mus musculus, Rattus norvegicus) IHC (Mus musculus, Rattus norvegicus)

Dilution:

WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com