Background:

Bombesin receptor subtype-3 (BRS-3) is an integral membrane protein belonging to the G protein-coupled receptor 1 family. The gene encoding for the BRS-3 protein maps against chromosome Xq26.3. BRS-3 is important in sperm cell division, maturation and function. Its actions are mediated by G protein interactions which activate a phosphatidylinositol-calcium second messenger system. BRS-3 is expressed in germ cells in testis and in lung carcinoma cells. Unlike other bombesin proteins, BRS-3 does not seem to be detected in the gut and central nervous system, but has been found in rat gastrointestinal tract. Mice lacking the gene encoding for BRS-3 develop obesity suggesting that BRS-3 may play a role in the regulation of plasma Insulin concentration.

Alternative names:

BRS3; Bombesin receptor subtype-3; BRS-3

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the Internal region of human BRS-3. at AA rangle； 140-220

Concentration:

1mg/ml

Applications:

WB, IHC, IF, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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