Bub1 Rabbit pAb ES7357
Specifications
| 50µl / 100µl |
Background:
BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in BUB1 have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Alternative names:
BUB1; BUB1L; Mitotic checkpoint serine/threonine-protein kinase BUB1; hBUB1; BUB1A
Clonality:
Polyclonal
Reactivity:
Human,Mouse
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the Internal region of human Bub1. at AA rangle; 220-300
Concentration:
1mg/ml
Applications:
IHC, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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