Cleaved-Caspase-1 (M211) Rabbit pAb ES7676
Specifications
| 50µl / 100µl |
Background:
CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products.
Alternative names:
CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
Clonality:
Polyclonal
Reactivity:
Human
Source:
Rabbit
Isotype:
Request info at info@sobekbio.com
Immunogen:
Synthesized peptide derived from the Internal region of human Caspase-1. at AA rangle; 170-250
Concentration:
1mg/ml
Applications:
IHC, ELISA
Recommende dilutions:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
