Background:

The protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for BCOR. A pseudogene of this gene is found on chromosome Y.

Classification:

Primary antibody

Alternative names:

BCOR; KIAA1575; BCL-6 corepressor; BCoR

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BCOR. AA range:1231-1280

Concentration:

1 mg/ml

Molecular weight:

192189

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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