Background:

BCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for BCL7A.

Classification:

Primary antibody

Alternative names:

BCL7A; B-cell CLL/lymphoma 7 protein family member A

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BCL7A. AA range:21-70

Concentration:

1 mg/ml

Molecular weight:

22810

Applications:

WB, ELISA

Storage:

-20°C for one year

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