Background:

The protein (arginine vasopressin receptor 1B) encoded by AVPR1B acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of AVPR1B has been reported but its function is not known.

Classification:

Primary antibody

Alternative names:

AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324

Concentration:

1 mg/ml

Molecular weight:

46971

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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