Background:

ATRIP encodes an essential component of the DNA damage checkpoint. The encoded protein (ATR interacting protein) binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

Classification:

Primary antibody

Alternative names:

ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ATRIP. AA range:34-83

Concentration:

1 mg/ml

Molecular weight:

85838

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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