Background:

The Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

ARHGEF9; ARHDH9; KIAA0424; Rho guanine nucleotide exchange factor 9; Collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARHGEF9. AA range:399-448

Concentration:

1 mg/ml

Molecular weight:

60982

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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