Background:

ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10

Species reactivity:

Human;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388

Concentration:

1 mg/ml

Molecular weight:

151612

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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