Background:

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Classification:

Primary antibody

Alternative names:

ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARG2. AA range:305-354

Concentration:

1 mg/ml

Molecular weight:

38578

Applications:

WB, ELISA

Storage:

-20°C for one year

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