Background:

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by ARG1, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

ARG1; Arginase-1; Liver-type arginase; Type I arginase

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARG1. AA range:61-110

Concentration:

1 mg/ml

Molecular weight:

34735

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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