Background:

ABL2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. Abelson tyrosine-protein kinase 2 is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

ABL2; ABLL; ARG; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human ABL2. AA range:601-650

Concentration:

1 mg/ml

Molecular weight:

128343

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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