Background:

APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Classification:

Primary antibody

Alternative names:

APLP1; Amyloid-like protein 1; APLP; APLP-1

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from APLP-1 . at AA range: 360-440

Concentration:

1 mg/ml

Molecular weight:

72176

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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