Background:

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Classification:

Primary antibody

Alternative names:

AMPD1; AMP deaminase 1; AMP deaminase isoform M; Myoadenylate deaminase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human AMPD1. AA range:261-310

Concentration:

1 mg/ml

Molecular weight:

86490

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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