Background:

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP1 encodes a member of the AKAP family. The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Classification:

Primary antibody

Alternative names:

AKAP1; AKAP149; PRKA1; A-kinase anchor protein 1; mitochondrial; A-kinase anchor protein 149 kDa; AKAP 149; Dual specificity A-kinase-anchoring protein 1; D-AKAP-1; Protein kinase A-anchoring protein

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human AKAP1. AA range:281-330

Concentration:

1 mg/ml

Molecular weight:

97342

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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