Background:

ADARB1 encodes the enzyme (adenosine deaminase, RNA specific B1) responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of ADARB1 results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Classification:

Primary antibody

Alternative names:

ADARB1; ADAR2; DRADA2; RED1; Double-stranded RNA-specific editase 1; RNA-editing deaminase 1; RNA-editing enzyme 1; dsRNA adenosine deaminase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ADARB1. AA range:481-530

Concentration:

1 mg/ml

Molecular weight:

80763

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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