Background:

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Classification:

Primary antibody

Alternative names:

ACR; ACRS; Acrosin

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Acrosin . at AA range: 40-120

Concentration:

1 mg/ml

Molecular weight:

45847

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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