Background:

EPAS1 (endothelial PAS domain protein 1) encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in EPAS1 are associated with erythrocytosis familial type 4.

Classification:

Primary antibody

Alternative names:

endothelial PAS domain protein 1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized acetyl-peptide of Acetyl-EPAS-1 (K385)

Concentration:

1 mg/ml

Molecular weight:

96459

Applications:

WB, ELISA

Storage:

-20°C for one year

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