Background:

TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for TNFAIP3.

Classification:

Primary antibody

Alternative names:

TNFAIP3; OTUD7C; Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TNAP3. AA range:321-370

Concentration:

1 mg/ml

Molecular weight:

89614

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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