Background:

The elongation factor-1 complex is composed of two subunits, EF-1 α1 (elongation factor 1-alpha 1) and EF-1 α2 (elongation factor 1-alpha 2), and is responsible for the delivery of aminoacyl tRNAs to the ribosome. EF-1 α1 is expressed predominately in brain, placenta, lung, liver, kidney and pancreas, while EF-1 α2 is highly expressed in heart, brain and skeletal muscle. Both EF-1 α1 and α2 localize to the nucleus and belong to the GTP-binding elongation factor family. The gene encoding EF-1 α2, which maps to human chromosome 20q13.3, may play a role in the development of ovarian cancer, while the EF-1 α1 gene, mapping to chromosome 6Q14.1, is commonly present as an autoantigen in patients with Felty syndrome. Felty syndrome is a disorder characterized by rheumatoid arthritis, a swollen spleen, decreased white blood cell count, and increased susceptibility to infection.

Specificity:

eEF1A1 polyclonal antibody detects endogenous levels of eEF1A1 protein.

Alternative names:

EF-1-alpha-1, EF-Tu, eEF1A-1, EEF1A1, EEF1A, EF1A, LENG7, CCS 3, CCS3, Cervical cancer suppressor 3, chunp6927, CTCL tumor antigen, EE1A1, EEF 1, EEF1A, eEF1A-1, EEF1A1, EF-1-alpha-1, EF-Tu, EF1A, EF1a like protein, EF1A1, Elongation factor 1 alpha subunit, Elongation factor 1-alpha 1, Elongation factor Tu, Eukaryotic elongation factor 1 A-1, Eukaryotic translation elongation factor 1 alpha 1, Eukaryotic translation elongation factor 1 alpha 1 like 14, Glucocorticoid receptor AF 1 specific elongation factor, GRAF 1EF, HNGC:16303, ik:tdsubc_2a3, ik:tdsubc_2b3, LENG7, Leukocyte receptor cluster (LRC) member 7, Leukocyte receptor cluster member 7, Prostate tumor inducing protein 1, PTI1, tdsubc_2a3, Translation elongation factor 1 alpha 1 like 14, wu:fa91c07, wu:fa94b03, wu:fi13b09, xx:tdsubc_2a3, xx:tdsubc_2b3,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

50 kDa

Applications:

WB ICC IF IHC FC IP

Usage:

WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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